On a related note, as of recent versions, Sunshine and Moonlight stable releases support 4:4:4 chroma subsampling and bitrates up to 500Mbit/s with HEVC, which results in almost indistinguishable image quality compared to native output[2]. Bitrates that high are unusual in normal content, but at least Apple's Media Engine (on M-series Macs) appears to be capable of decoding it.
[1] Here is a pretty good solution that piggybacks off of Parsec's driver, which is fully signed, though its EDID lacks HDR support. The project also includes a C header file for custom implementations: https://github.com/nomi-san/parsec-vdd
[2] Note: I found that I had to enable 10-bit color streaming (which is available when using Parsec's driver) to get rid of some gradient banding that isn't present in native 8-bit. I suspect it's some encoder and/or color space issue.