It is not meant to be literally interpreted as attributing contingent political preferences to the universe, but rather to be a (politically biased) statement on the tendency of conservatives to categorically deny reality and reframe it as leftist propaganda whenever it contradicts their narrative. One can extend this "bias" to include the rejection of mainstream scientific and historical narratives as "woke" by the right in a more modern context.
[0] https://en.wikipedia.org/wiki/Stephen_Colbert_at_the_2006_Wh...
> There are two distinct ways to be politically moderate: on purpose and by accident. Intentional moderates are trimmers, deliberately choosing a position mid-way between the extremes of right and left. Accidental moderates end up in the middle, on average, because they make up their own minds about each question, and the far right and far left are roughly equally wrong.
Both sides just pick and trumpet the hard truths that they like.