Reading e.g. the 13% perf regression in simdjson from disabling UB:
A simpler alternative is to compile the program with LTO. We confirmed that LLVM’s inter-procedural analyses can propagate both alignment and dereferenceability information for this function, which allows the LTO build to recover the performance loss.
"can" is doing a lot of heavy-lifting here. Guaranteeing expected optimizations "will" be applied are hard-enough, without leaving it entirely to an easily-derailed indirect side-effect.