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Comment by pfdietz | Hacker News Reader

One disturbing recent discovery is that a strain of E. coli produces a genotoxin, colibactin, that could be the cause of the doubling in colon cancer among those under age 55 in the last 20 years.

https://www.opb.org/article/2025/05/01/gut-bacteria-may-play...

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How many people took Zantac (ranitidine) the highly spammed H2 blocker? https://www.nfcr.org/blog/3-common-heartburn-drugs-are-assoc...

Doctors don't ask about this. People still take Prilosec, and it's acknowledged that it causes cancer. You get what you give: confirmation bias.

Edit: The essential problem is that ranitidine isn't shelf-stable. This could explain some problems with other theraputics which we won't name to avoid downvoting / politics.

> and it's acknowledged that it causes cancer.

This is not acknowledged as demonstrated, the studies are contradictory and observational.

It is acknowledged that nitrosamines cause cancer. It is acknowledged that ranitidine breaks down on the shelf to nitrosamines: this wasn't discovered by the FDA or another government agency, it was discovered by a mail-order, compounding pharmacy which also tests ingredients. Their discovery led to ranitidine being recalled.

As for prilosec: the cancer risk is acknowledged in the packaging.

I wasn't talking about ranitidine, so I don't know why you brought that up.

I don't see anything about cancer in the product information for Prilosec.

https://www.amazon.com/Prilosec-OTC-Heartburn-Medicine-Versi...

Perhaps you mean in California, where everything + dog has a cancer warning by law?

Squeeze this lemon till the juice come out: https://www.verywellhealth.com/does-omeprazole-cause-cancer-...

ddg:prilosec cancer

Buy some. Read the packaging. Fuck Amazon.

I have a package of generic omeprazole right in front of me. There is no cancer warning.

Fix it, so somebody doesn't have to die like you.

Your effort to fabricate evidence having failed, we see you didn't actually need evidence to reach your conclusion anyway.

Hey. I brought up ranitidine because it is specifically associated with nitrosamines, and nitrosamines cause colon cancer. No redirect: colon cancer. You take issue with prilosec being admitted to this debate, then that would be because ion pump moderators cause stomach cancer. My bad: stomach cancer irrelevant to you.

You can't see ranitidine when it farts in your face: nitrosamines cause colon cancer. Why is that not relevant? Why is that not potentially more relevant than foo foo microbes? (By the way, I eat sour cream or yogurt when I eat meat or take e.g. glucosamine. YMMV.)

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