FWIW, that was also an initial concern of mine. Almost three years later, i've never once had an issue with running my pi-hole over wifi.
on good wifi with no interference you can get good 2ms avg and 0.2-0.4 ms SD ping distribution.
ethernet will have 0.2 ms avg and 0.01 SD
it's the outliers that will cause headaches, when there is radio interference.
wifi is a dynamic system with every base station migrating bands for interference.
i opine that there's no _functional_ difference between those speeds for purposes of a home LAN. Both values are far below humans' ability to perceive the difference.
I mostly used USB as an experiment and I didn't know what else to do with the regular-zero
Very cool how a $5 board could work so well! I was glad to see your post.