One possibility is a file.py that is called by your framework. The interface could be something like

  def doth_match(*args):
    return True  # the predicate

  def doeth_thou(*args):
    # processing things
    return {}  # status object for example

The framework loops and checks the first function; if true, then execute the second function. And then break or continue for other rule files (or objects).

There could be multiple files rule1.py, rule2.py, etc that check and do different things.