The real difference is whether than decentralized, loosely coupled system is run by and owned by a single corporation, or not.
It's the design of the system itself that determines latency, not the centralized vs. decentralized argument.
You're speaking as if twitter.com is a single giant machine on a single IP address. In fact, it's thousands of loosely coupled machines and services all working in tandem across nearly the entire globe. Sounds like a typical decentralized system to me.