Lisps support OO like you wouldn’t believe: https://lispcookbook.github.io/cl-cookbook/clos.html

You could write DSLs for them, but you could just as easily do it within the existing syntax. Which is exactly how all the popular lisp implementations of OO, concurrency and type checking work in practice.

Many of them do use macros. But that's not about creating a special language; that's about moving expensive computations and checks that can be done statically to compile time where they belong.