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FWIW, I've been running a system with roughly 100K users, about 25 qps on average, with a single SQLite file for several years. No issues with data.

That's... pretty amazing. It sounds crazy to me, I'm obsessive about hourly backups, but do you use something like Litestream to keep copies?

> searchcode.com’s SQLite database is probably one of the largest in the world, at least for a public facing website. It’s actual size is 6.4 TB.

Yep, we use Litestream. It's been very reliable.