Even with that level of target knowledge (I suspect the US has the investment in the sensor-targeting links to be able to use satellites to know within cm where planes were within a five minute window, but am not sure about other nations) you'd want to have some that were available for later re-targeting to handle misses. Nuclear weapons war plans solve this by relentlessly re-targeting again and again (declassified 1960's USAF war plans called for over 70 different missiles to hit Moscow alone) but with the smaller damage radius of conventional weapons you either end up with a second strike to make sure you get all the survivors of the first strike- or have a trained human who knows the targeting priority in the loop available to update targeting on the fly.

GPS can't be relied on in that heavily denied area. And indeed the screenshots show drones in failsafe mode.