Anyone better than me in pharmacology able to explain how suzetrigine compares to (high dosage?) ambroxol?
They are both Nav1.8 blockers, but in Germany you can get lots of ambroxol for cheap and OTC.
They are both Nav1.8 blockers, but in Germany you can get lots of ambroxol for cheap and OTC.
Really appreciate you mentioning it
It potentiates antibiotic effect in lung infections, including tuberculosis, treats painful hyperacusis, trigeminal neuralgia, neuropathic pain, parkinson, gaucher disease...
...and what's this? We have a surprise guest!
Ambroxol significantly reduces snoring and thus suddenly becomes a candidate for a medication half the population should take!
https://www.researchgate.net/publication/314424871_Evaluatio...
It's one of those drugs that deserves way bigger interest than it gets.
https://images2.imgbox.com/e1/b7/YaB8gjLI_o.png
but apparently the problem with ambroxol vs suzetrigine
is it is not as selective on the ion channel and not as strong (needs megadose to do similar)
I cannot remember the drugs offhand but this is the same problem with other old generics for other kinds of targets
suzetrigine won't be generic for years which is a shame