It's certainly not that bad if you have uMatrix to do it with, but I haven't found a reasonable way to do it on mobile. uMatrix does work on Firefox Mobile but the UI is only semi functional.
Using Firefox Add-Ons on a "smartphone" sucks because one has to access every Add-On interface via an Extensions menu.
In that sense _all_ Add-Ons are only semi-functional.
I use multiple layers: uMatrix + NetGuard + Nebulo "DNS Rules", at the least. Thus I have at least three opportunities where I can block lookups for and requests to Google domains.
https://github.com/gorhill/uBlock/wiki/Advanced-settings
Having tried both, IMHO they do not do exactly the same thing. One is pattern-based, the other is host-based. As such, one can use them together, simultaneously.
Basically uMatrix is so donor to use that anybody can use it. The equivalent uBO section is so complicated that I feel I need to take a master degree in that subject.
Also, deleting everything when Firefox closes. It's a little annoying to re-login to everything every day, but again, they are banking on this inconvenience to fuck you over and I refuse to let them win. It becomes part of the routine easily enough.