I have driven up to 6 hours at a time, but I'm in hyper-focus mode the whole time and it takes everything I have to stay locked into that focus so I don't die. I think all the time about moving somewhere where I don't need a car. I hate driving and always have.
I recently found out I have ADHD. I haven't tried meds yet (but am having my first meeting with someone tomorrow to explore it as an option). I'm wondering if this will make driving more tolerable for me. It wasn't even something I thought about before this thread.
However, as I made that drive more, it got worse. Traffic was usually heavier, and things didn’t go as well with a lot of traffic. Some of it was how it acted, and some of it were trust issues with it. When traffic picked up or other cars did things around me, I’d switch back to manual control. After a while, I was using manual control the whole time… and then eventually just took the train, because I couldn’t tolerate driving myself anymore.
To be honest, now that I'm medicated I think I could at least do 5 hours without stopping. I might need some snacks though - the amount of sugar I've been consuming lately is unnatural
Having a car with lane centering cruise control also helps a ton, at least where I live. Not having to micro-manage a car for several hours when you're on a long drive reduces the cognitive load.