The stdlib. It has some great parts and overall is just good enough (and desire to not break everyone's code) to not cause revolt and wholesale replacement.
FTPlib is atrocious.
httplib/urlib mess -> requests
os os.path, shutil subprocess is a ridiculous mish-mash of legacy, obscurity and surprising behavior. One example. os.mkdir (but only the leaf, and exception if it exists), want mkdir -p behavior. Is that an option to os.mkdir, fuck no! We need a whole new function for such dramatically different feature. Must be called mkdirs, fuck no! That would be too easy to remember and no one every look at our beautiful docs. os.makedirs is the obvious choice.