Using a mega-framework there could be a point where I would have to work around the limitations while using a micro-framework just means that there could be the point that I invest time (implementing, maintaining, maybe even some troubles updating parts of the system to new versions,...) implementing something that a mega-framework provides out of the box.
For the sake of fun I wrote a basic implementation using Django and PostgreSQL and one using Flask and Redis. I did not use a stopwatch but I would say that it took the same amount of time.
The only difference? In my experience I will have an easier time adding a feature quickly thanks to all the batteries Django already includes.