Similarly, for every chemical and nuclear reaction, when something is gained, something else is lost. For example, when two ions bond covalently by sharing electrons, a new molecule is gained, but the two ions are no longer what they previously were. So there is a correlation between gain of reaction products and loss of reactants.
But perhaps such analogies cannot be found everywhere in theoretical physics. Perhaps such a non-correlation would be a sign of a novel discovery, or a sign that a theory is physically invalid. It could be a signal of something for sure.