We recently evaluated DNS options for our ~800 domains we host DNS for and decided to go with DNSMadeEasy. We're not switched over yet but the deciding factor for me was they're an anycast network and can offer a lot of cool regional responding if we grow to that size. We want to use vanity domains, e.g. ns1,2.ourcompany.com so w/ DNSimple that's only two locations that need to be DDoSed or fail and our sites are down.