Problem 1 in Stanford's crypto class [1]:
Data compression is often used in data storage or transmission. Suppose you want to use data compression in conjunction with encryption. Does it make more sense to
A. Compress the data and then encrypt the result, or
B. Encrypt the data and then compress the result.
Now we know the correct answer is Neither.
[1] http://crypto.stanford.edu/~dabo/cs255/hw_and_proj/hw1.pdf