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Being pursued since UNCOL in 1958, each attempt eventually only works out for a specific set of languages, due to politics or market forces.

Hm. SPIR-V is a standard IR, but AFAIU not really the kind of IR that you need for communication inside a compiler. It wasn't designed for that.

WASM ?

WASM !

It's probably not too bad of an option these days tbf. Are there any optimising WASM compilers that can get close to native performance?