I've been using pdf.js for a while on my Windows box (where it is enabled by default on the FF beta channel) and it has performed remarkably well. Sometimes it's a bit slower than Adobe Reader or messes up colour or formatting, but on the whole I've quite enjoyed using it.
[0]: https://svn.torproject.org/svn/projects/design-paper/tor-des...
Note that the text in [0] doesn't scale properly, and the page previews in the navigation pane just show garbled text. Usable, but only just.