Not directly, but when you have devs who only know how to build with the framework and don’t have a grip on what’s going on under the hood or how it all interacts in the browser environment (increasingly common), performance is sure to take a hit.
Even languages or environments that try to "steer the developer into the correct direction" have only really managed it when the new direction is something they already might've chosen to write. Otherwise, you just end up with many square pegs filed down to fit in round holes.