> WebAssembly apps tend to run slower in 64-bit mode than they do in 32-bit mode. This performance penalty depends on the workload, but it can range from just 10% to over 100%—a 2x slowdown just from changing your pointer size.
> This is not simply due to a lack of optimization. Instead, the performance of Memory64 is restricted by hardware, operating systems, and the design of WebAssembly itself.
https://spidermonkey.dev/blog/2025/01/15/is-memory64-actuall...