Now it's just Iran/Cuba/North Korea, but you're essentially letting the increasingly aggressive American government decide who can or cannot publish software. The Americans are not afraid of adding their political enemies from allied countries to the sanction list, as can be seen when they decided to go after the judge in the Israel genocide case. Who knows who will be next now that they're blatantly cracking down on free speech.
The Apple app store/Google Play/Microsoft Store are great conveniences, but they must never be the only way to access software on your device. Apple's EU exception falls short for still requiring an Apple account to pay fees that no judge will accept when the first lawsuit hits. Sure, Epic Games has offered to pay those fees just to spite Apple, but Epic can only pay those fees to people they're allowed to pay.