Yes, it's not possible to do it the same way, because what made x86 successful in their application is that x86 was remarkably RISC-y in actual behaviour compared to 68k or VAX.

The main reason for that is that x86 code, outside of being register poor leading to lots of stack etc. use, decomposes most "ciscy" operations into LEA (inlined in pipeline) + memory access + actual operation.

VAX (and to lesser extent, m68k and others) had multiple indirections just to get the operands right, way more than what is essentially single LEA instruction. The most complex VAX instructions could have been ignored as "this is super slow one and rarely used", but the burden of handling the indirections remain, including possible huge memory latency costs.