Personally, I would never agree to give up SMP CPU coherency. Multiprocessor systems are hard enough to debug with hardware cache coherency that adding in entirely new unpredictable non-deterministic behaviour would lead to more developers losing the rest of their hair prematurely. And it would likely introduce an entirely new class of security issues that nobody ever imagined that would require even worse performance draining software workarounds.
Some things are best done in hardware.