Aren't treaties with the US meaningless by default, unless ratified by 3/4th of Congress?
The other three parts all concern areas not delegated to the EU. To become law, all three parts have to be approved by the EU parliament and the EU council (which consists of the heads of the executives of the member states) and the local parliaments of the member states. Depending on local law, even regional parliaments have to approve it (Belgium is such a state). The final implementation of Mercosur is not expected before 2028.