To put some numbers to trying to develop a single therapy (where candidates etc. will fail as you try them)
- Plan to sink $180-500M+ just in R&D
- Factor in failures, regulatory, clinical, recruitment, phase 1/2 trials and you arrive very quickly around $1.3-2.1 BILLION USD per therapy approved.
...there is a 90% chance that you will spend that $1B+ - and it will fail completely.
https://www.nature.com/articles/d41573-020-00043-x
https://greenfieldchemical.com/2023/08/10/the-staggering-cos...