I think when programmers are introduced to languages, most grok procedural ones easier than functional ones, hence Lisp and its derivatives have struggled in popularity for decades.
But with Lisps isn't it the case that statement 1 can be immutable while the next statement 2 is mutable? In other words it mixes mutable and immutable calls into the same program-file without really isolating them from each other in any way. And that means if one part of the program is "impure", so is all of it. You can't isolate those parts except by following a convention, but conventions are not something that it enforces. And you can't know which parts of your program are pure except by reading the code-statements in detail. Am I right?
Ultimately I think it might just be fads. Object oriented programming came along at the same time as the web, when the demand for programmers grew dramatically. That may have crystallized OO and imperative languages as the "default" style. Would be interesting to see the alternate universe where JavaScript actually was a Lisp.