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Comment by xtracto | Hacker News Reader

Several members of my family are into glp-1 both for glucose control and for weight loss. Taking different brands (wegovy, ozempic and others.) They all mention.th terrible secondary effects when you eat something "forbidden" (tacos, cake or icecream e.g.) .

  Also It causes constipation apparently,  which for most of them is not that much of an issue, but given that I've IBS-C, I'm happy to not have to take it.

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I'm surprised that tacos are a big deal. I'd have thought that the filling (meat, cheese, veggies, maybe beans) would mostly outweigh the carbs from the shell.

I take a glp-1 and suffer no ill effects when I eat something "forbidden".

More anecdata, my spouse and I have been on Mounjaro since Jan 2025 guided by private health insurance.

I have suffered almost the entire gamut of side effects from the beginning until I tried split dosing twice a week, and even then there’s still the occasional instance of me learning that I should not have eaten that and the following 9 hours are going to revolve around stomach pain.

My partner’s journey on the other hand has been smooth sailing the entire time.

YMMV, do your own research but definitely double check any search results with your doctor first… lots of urban myths going around.

I do recommend it though, I am the healthiest I’ve been in literally 10 years.

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