why would it matter what's in your stomach? caffeine goes pretty quickly to the blood stream, right?
https://www.sciencedirect.com/science/article/abs/pii/S14402...
Another effect of caffeine is as an adenosine re-uptake antagonist. Adenosine levels are usually low in the morning, so the effect is small. Later in the day, it can have a bigger effect on how alert you feel.