People typically live only once, so I want to make the best use out of my time. Thus I would prefer to write (prototype) in ruby or python, before considering moving to a faster language (but often it is not worth it; at home, if a java executable takes 0.2 seconds to delete 1000 files and the ruby script takes 2.3 seconds, I really don't care, even more so as I may be multitasking and having tons of tabs open in KDE konsole anyway, but for a company doing business, speed may matter much more).
It is a great skill to be able to maximize for speed. Ideally I'd love to have that in the same language. I haven't found one that really manages to bridge the "scripting" world with the compiled world. Every time someone tries it, the language is just awful in its design. I am beginning to think it is just not possible.