SF embraces tech and in general (politics, etc) has a culture of being willing to try new things. Overall tech hostility is low, but the city becoming a testbed for projects like Waymo is possibly changing that. There is a continuous argument that their free-spirited culture has been cannibalized by tech.
Seattle feels like the complete opposite. Resistant to change, resistant to trying things, and if you say you work in tech you're now a "techbro" and met with eyerolls. This is in part because in Seattle if you are a "techbro" you work for one of the megacorps whereas in SF a "techbro" could be working for any number of cool startups.
As you mentioned, Seattle has also been taken over by said megacorps which has colored the impressions of everyone. When you have entire city blocks taken over by Microsoft/Amazon and the roads congested by them it definitely has some negative domino effects.
As an aside, on TV we in the Seattle area get ads about how much Amazon has been doing for the community. Definitely some PR campaign to keep local hostility low.