I don’t think it will ever make sense; you can buy so much cloud based usage for this type of price.
From my perspective, the biggest problem is that I am just not going to be using it 24/7. Which means I’m not getting nearly as much value out of it as the cloud based vendors do from their hardware.
Last but not least, if I want to run queries against open source models, I prefer to use a provider like Groq or Cerebras as it’s extremely convenient to have the query results nearly instantly.