The infamous MCGA/"VGA" mode 13h had pixels with an aspect ratio 6:5, while 320 x 240 Mode X was square (1:1).
I still remember the unchained offset calculation for the memory offset for pixel memory access before the era of U and V pipes and many optimizing compiler passes:
unsigned short offset = (((y << 2) + y) << 6) + x;
unsigned char far *ptr = (unsigned char far*)MK_FP(0xA000, offset);
// IIRC: #define MK_FP(seg, off) ((void far *)((unsigned long)(seg) << 16 | (unsigned long)(off))) // far pointers != linear address
In real-mode (linear): 0xa0000 + (320 * y) + x