I've always wanted to do music recording on Linux (literally since the 90s). The fact that my preferred DAW (Reaper) has long been native to Linux has tempted me. But I have Universal Audio "Apollo" interface and have bought into their whole ecosystem which is very good and runs really great on my mac.
If I made the plunge I would get an RME USB audio interface and use Reaper, maybe play around with Bitwig which is also native on Linux. I don't think I would mess with WINE, regardless of other's success stories with it.
I'm glad to see where things have gone in recent years though