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Comment by nwienert | Hacker News Reader

> Not really

This made me actually laugh. A drug that cures obesity and addiction alone would be a wonder drug.

This one also improves about a hundred odd immune disorders, including being a better general allergy drug than just about anything. My own extremely rare and terribly painful immune disorder is basically entirely cured by it - it completely changed my life, making even sleeping far better. But not just me, I have friends who have lifelong terrible allergies gone, lifelong pack-a-day smoking addictions completely gone, and so on...

"Not really" is truly either the most pessimistic take I've ever heard, or hopefully just completely misinformed.

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> A drug that cures obesity and addiction alone would be a wonder drug.

A drug that influences a hormone causing effects on everything that hormone is involved in shouldn't be considered a wonder drug, it should be expected functionality.

It's only a wonder drug that does all these miraculous things if you think GLP-1 is only a weight management hormone. It's not, and you should expect effects anywhere it is involved in. A short list of tissues we know GLP-1 is involved in processes is:

- heart - tongue - adipose tissue - muscles - bones - kidneys - liver - lungs

Effects on these aren't miracles, they should be expected.

I am happy to hear you saw so many improvements, but it's because you had an issue with a hormone that is involved in a lot of things in the body. So it was going to express a lot of problems. It's not surprising that you see a lot of improvements when you begin to manage the underlying cause.

The fact you assume to know what my issue is is wild, and especially since you're just completely wrong - I have no direct GLP-1 issue, my levels are normal.

It's clear you have no idea what you're talking about. Every single case I'm talking about outside weight loss has nothing to do with having a deficiency of that hormone, rather it's fixed by the hormone raising. And given it was impossible to do otherwise, it's a wonder drug, of course. You don't really define wonder by how simple it is, but by the effects, which are tremendously beneficial to many.

Further, I stand by my prediction that in the long run the vast majority of why this drug will be considered an once-a-generation discovery, is not due to weight loss or appetite control, but in fact it's seeming broad spectrum benefits across many systems. And actually your list of effects it has are interesting, because if you investigate deeply the studies published, you'll find that the results are overwhelmingly positive - brain, heart, many organs.

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