This is excellent advice. One of the challenges is that really big things can become overwhelming and intimidating, but small things are quite doable. When I was writing a column for JavaWorld I remember how 'hard' it was to write a 1500 - 2000 word column, but 'easy' to write a 2000 word email. Michael O'Connell, my editor there, suggested that I just write an email and let the editors make it into the column. I decided that was stepping too far back, but I could effectively break my writer's block by emailing myself the question I wanted to answer and then approaching the first draft as an email.
I would expect that much the same happens between 'startups' and 'weekend projects.' If you build a small project for the weekend you don't really care that you will be done on Sunday (or Monday perhaps :-) and that will be that. A 'startup' on the other hand that is the first step and then you have to drive traffic, and get buzz, raise funding etc etc. So it stops being a 'weekend project' and becomes the start of huge pile of work. Yuck!