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For example, running very large trials in a short time is very high effort.

Worth it

It's a trade-off: better info versus handling an immediate crisis. If it's not an immediate crisis, you can take more time.

Engineering is trade-offs.

People are dying of these diseases every day

And killing them with an insufficiently tested treatment is not optimal.

For patients. But maybe not to the companies which would have to pay for these large expedited trials