the 6502 package would probably shrink to use something like a BGA package, and you could probably make some kind of "multicore" system using 6502 processors. I'm not knowledgeable enough to say how feasible that would be, but you could probably use something with shared memory regions to pass data between them and run code in parallel.

If you are absolutely limited to 6502 DIP chips, there would probably be more prevalence of large mainframe systems and single 6502-based "terminals"/"thin clients". The mainframes could use systems similar to the Transputer or the Connection Machine to use large amounts of (comparatively) low-power processors to make a single, more powerful computer. They both used custom processors, with the Connection Machine in the early 80s and the Transputer in the late 70s. You could probably reasonably easily create a "graphics card" style system, comprised of many 6502 cores in a SIMD configuration.

I don't know how easy it would be to implement wifi or ethernet with only 6502 chips, so communications with the mainframe might be quite slow