Science is and always was incremental. The breakthroughs come from truly unforeseeable places. It takes seemingly niche and unprofitable and incremental research like studying bacteria living in volcano vents, for us to have PCR.
VCs expect a sliver of their companies to become Unicorns, we understand it to be a numbers game. That grace is given to entrepreneurs but scientists need to grovel for cash and endlessly show that their research is "translatable" or sufficiently impactful.
Sorry, I've heard this one too many times before. Thanks for your contribution to our world's knowledge, I hope you value it as much as I do.