All three of these suggestions are likely true. I’ve never done Ketamine but I’ve heard it can seriously degrade the user’s “quality control” of their ideas, meaning that ideas that they have, or ideas they get from others, that are intellectually subpar appear to be quite brilliant. The dissociation is also helpful for overcoming moral qualms if they were ever present.

Combine that with speed and a insular SV culture steeped in the ideology of Ayn Rand and Nick Land (who likely suffered from amphetamine psychosis) and you get something like this Palantir manifesto.

I would feel sorry for them if they weren’t building skynet.

"21. Some cultures have produced vital advances; others remain dysfunctional and regressive. All cultures are now equal. Criticism and value judgments are forbidden. Yet this new dogma glosses over the fact that certain cultures and indeed subcultures . . . have produced wonders. Others have proven middling, and worse, regressive and harmful."

This is incredibly racist, ending thinking at "well, some types of people just suck, and other types of people are better" without considering the complex and nuanced factors over the course of human history that result with the world we have today.