It acts on the KOR receptors instead of the MOR receptor, which most openly act on. But it’s not like you’re going to be cured from opioid addiction. You’re just replacing one opioid with another that doesn’t affect the respiratory system.
Your comment also seems to imply that this treatment involves consuming ibogaine habitually or regularly
The protocol for ibogaine treatment, according to the article and the experiments being done, do not have this requirement.
Like other treatments involving psychedelics and hallucinogens, the protocol here is that a one-off treatment, a single dose, results in meaningful improvements in both addictive behaviors and PTSD symptoms a month later and potentially longer
This is not the same as something like methadone or naltrexone, which _are_ what you describe: replacing a more harmful opiate with a less harmful one.
Opioid use has been associated with numerous psychiatric symptoms, including dissociative symptoms.
Menthol, for example, only activates the kappa receptor: accidentally overdosing on pure menthol felt to me like immediate doom was approaching and nothing would ever again be fine.
I don’t eat anything menthol-flavored any more. It seems like an operant conditioning agent masquerading as a flavor.