Orbital compute is technically very feasible. We’re not talking about a datacenter-sized structure, but a lot of rack-sized satellites connected by laser links. SpaceX has gotten pretty good at building, launching, and managing large constellations.
Economically it obviously it has challenges, but there are some advantages (6x solar production, free real estate, less regulation, arguably simpler cooling) to balance the extra costs (launch, radiators, lack of access for maintenance, limited lifespan, etc).