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Has anyone made a generic Dropbox<->S3 bucket sync client yet?

Yes. We created Backup Box back in March to solve this problem. https://mybackupbox.com

We have also released our technology as an API at http://mover.io

Feedback is welcome!

Mover.io looks like a great idea. I've been fiddling about with S3 and FTP wrappers, so this looks helpful. I'm looking forward to my API key.