I have two major contentions. First, I'm a neuroscientist by training, so hearing anything related to "upload my brain" just makes me weep. The only realistic way to "upload your brain" is to pump your body full of fixatives (paraformaldehyde), section it on a cryostat and then perform electron microscopy across every single slice. Then put it all back together (fixing skewing artifacts, etc) on a computer.
THEN make a simulation out of it, where every atom of your body is replicated with pristine accuracy. Otherwise you are not yourself anymore.
I'm not saying it's impossible. I'm saying it's so far from likely that being near-immortal due to bio-enhancements is almost certainly more practical. Or you can develop some "scanning ray gun" which does the same thing without killing you first, I suppose.
Second, the whole notion of "exponentially increasing intelligence" I find silly. Are we more intelligent than homo sapiens 3000 years ago? Perhaps more scholarly, more literate, more capable of engineering complex systems. But our inherent, base intelligence is not any different. Just applied to different problems and starting at different bases of knowledge.
Edit: Musing on this, I find a "Matrix"-style hostile takeover of highly intelligent AI much more likely than humans "transcending" into some super-computing cloud of blissful hyperintelligence. That's seems much more likely than humans ever fully shucking our meat bag bodies.