Can we say for certain that doing so would not have an unintended side effect, given how complex the biodome is? If not, then likely no.
If the SO2 brings about destruction sooner, I'm of the camp that "well, we were destined for death anyway...".
Possible unintended side effects is better than "everyone dies".
Ten years ago, I was saying we should experiment with it on a small scale so that if it does become necessary, we're not shooting blind, but even then the doomers were opposed because of "risks". You know what else has risks? Unmitigated climate change!