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By a LOT. It would expose the data Windows keeps isolated using virtualization based security.

Does this mean the exploit can be used in a VM to get access to the host machine?

Not necessarily. A VM doesn't have a "real" DMA controller, and this exploit is specific to a family of real hardware CPUs.

Its not to say that its not impressive, but its fairly isolated to a specific family of processors from 2013.

Oh, right. I forgot that DMA controllers are virtualized on VMs.