The low bandwidth / high latency lossy link problem is still a major issue. Cell phone service is sufficiently shitty in the area I live in that I have to use mosh to get a usable remote connection many times a year. Mosh is also quite useful while travelling! Got a crappy connection on a train or airplane? No problem. I have so much muscle memory with the mutt email client that nothing else has ever come close. Where's the equivalent of mutt's limit command in Thunderbird?
Try getting a usable VNC session when your cell phone hot spot is hitting 2-30 second ping times (yes -- thirty seconds) with only a handful of packets getting through.
Version 2 of the Amiga's operating system did a great thing in version 2 of AmigaOS which explicitly spelled out what conventions to apply (see Amiga User Interface Style Guide at https://archive.org/details/amiga-user-interface-style-guide). Modern GUIs that have weird meaningless buttons are infuriating. Even moreso when they lack obvious keyboard shortcuts.