Back in the 90's, there was a game called "Midtown Madness" by Microsft. They simulated SF and London very well. This game now takes it to another level.
Came here to say this - I have fond memories of playing Midtown Madness 2 as a kid (IIRC it came bundled with our new Windows ME family PC). I remember when I had the chance to visit SF in 2005 and I would recognize so many of the streets from playing the game. Good times.