I dropped QubesOS once exactly for that reason in the past but now I’m running it again on a separate computer.

Even with all its drawbacks, there is something really nice about being able to run different applications over Tor, VPN or plain internet simultaneously, the ability to isolate non-safe binaries and being able to backup your VMs easily.

I wish a similar distro would be made based on KVM so that the standard kernel could be used. It would be great for compatibility.